Centers & Institutes
Oxidative Stress Environmental Analysis Core Laboratory
The Oxidative Stress Environmental Analysis Core laboratory is located in the Innovation Center on the IU Bloomington Campus. The laboratory has established a number of measurements for assessing oxidative stress and damage in a variety of biological samples with excellent accuracy and reproducibly using state of the art LC-MSMS, GC, and PCR equipment.
The Klaunig Lab is involved in performing and publishing high-quality, peer-reviewed research in the areas of toxicology, carcinogenesis and toxicologic pathology. Our research has been devoted to understanding the mechanisms by which pharmaceuticals, other chemical agents and physical agents impact normal cellular and organ function.
Global Environmental Health Research Laboratory
Global Environmenta Health Research Laboratory is located in the Indiana University-Bloomington School of Public Health. Our mission is to conduct basic and applied interdisciplinary research focused on the environmental health challenges affecting rural and urban communities in Indiana, the U.S., the U.S.-Mexico Border, and abroad, especially Latin America. In addition to our main lab in the IUB-SPH, we maintain two field sites in northern Ecuador, one in the capital city of Quito and the other in a rural tropical rainforest area.
One of the lab’s major research lines is focused on the effects of air pollutant exposure on systemic inflammation, cardiorespiratory function, and other human health outcomes. We use portable equipment to measure indoor and ambient air quality including NanoScans (ultrafine PM) and DustTraks (PM10, PM2.5, PM1) and molecular biology and immunological techniques to assess inflammation, oxidative stress, arterial activation, arterial remodeling, and cardiorespiratory function. Another major research line involves infectious disease epidemiology, prevention and control, especially TB, leishmaniasis, Chagas’ and other parasitic diseases of public health importance. This work includes development and testing of anti-Leishmania vaccines, vector and reservoir ecology, and studies looking at the effect of climate change on the infectious disease dynamics. Other important research lines in the Global Environmental Health Lab includes studies of the impact of food insecurity on nutrition and health of women, children and their families and occupational health challenges of agricultural workers.